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DuoNeb® is the only FDA-approved combination medicine for COPD that comes in a single ready-to-use vial for nebulization. DuoNeb® contains albuterol and ipratropium — two of the most commonly prescribed bronchodilators for COPD.
In a third-party market research study of COPD patients, 80% of them said that nebulizing gives them a better quality of life than an MDI alone.1 Nebulizers are fast, effective, and very easy to use. They fit very well with your lifestyle. You can use your nebulizer:
  • at home
  • at work
  • when you travel
  • just about anywhere
DuoNeb® has clear advantages:
  • The combination of medicines in DuoNeb® is more effective and longer lasting than either medicine by itself.
  • DuoNeb contains two of the most commonly prescribed medicines for COPD in a single easy-to-use vial. This means no mixing in the pharmacy and less risk of contamination.
  • With DuoNeb®, you can receive the same amount of active medicine with up to 45% less solution.*

    *DuoNeb® unit dose is 3.0 mL total volume vs 2.5 mL ipratropium unit dose and 3.0 mL albuterol for 5.5 mL total volume.
1. Patient Assessment of Efficacy of Nebulizer Systems on Their Respiratory     Health.Maplewood, NJ: Safian Communications Inc.; 1995.
2. Dolovich MB, Ahrens RC, Hess DR, et al. Device selection and outcomes     of aerosol therapy: evidence-based guidelines. Chest. 2005;127:335-371.
About Inhalers and Nebulizers
Metered dose and dry powder inhalers can sometimes pose problems for people with COPD. For example, some find that they cannot hold their breath long enough for the medicine to get where it needs to go. Others find that having to activate the dispenser while breathing in is difficult. With an MDI or DPI, you must coordinate your breathing with the mechanics of the inhaler. This can be tricky if you have arthritis or simply breathe in too soon or too late. MDIs are quicker to use and highly portable, but require the most patient training to ensure coordination for proper use. Up to 70% of patients fail to use them properly.2
Nebulizers turn your medicine into a very fine mist. All you have to do is breathe normally and the medicine will be easily taken into your lungs. You can be confident that your medicine is getting where it needs to go.
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Please read this important safety information about DuoNeb®
DuoNeb® is indicated for the treatment of bronchospasm associated with COPD for patients requiring more than one bronchodilator. In a 12-week clinical study, the most common adverse reactions reported with DuoNeb® Inhalation Solution were chest pain, pharyngitis, diarrhea, bronchitis, nausea, and leg cramps.
Albuterol sulfate can have a significant cardiovascular effect, significant hypokalemia, and the potential life-threatening paradoxical bronchospasm. Caution is advised in patients with convulsive disorders, hyperthyroidism, diabetes mellitus, narrow-angle glaucoma, prostatic hypertrophy, or bladder-neck obstruction. Co-administration of DuoNeb® Inhalation Solution and other sympathomimetic agents may increase the risk of adverse cardiovascular effects.